| Tue Sep 20th,2011 | Birtley Town | v | Stockton Town | 0 - 1 |
| Tue Sep 20th,2011 | South Shields | v | Ryton & Crawcrook Albion | 3 - 2 |
| Wed Sep 21st,2011 | Belford House | v | Darlington CB | 2 - 3 |
| Wed Sep 21st,2011 | Consett | v | Hebburn Town | 4 - 1 |
| Wed Sep 21st,2011 | Darlington FC | v | Gateshead Leam Lane | 3 - 0 |
| Wed Sep 21st,2011 | Darlington RA | v | Jarrow Roofing BCA | 2 - 0 |
| Wed Sep 21st,2011 | Peterlee Town | v | Boldon CA | 2 - 1 |
| Wed Sep 21st,2011 | Ryhope CW | v | Easington Colliery | 3 - 2 |
| Wed Sep 21st,2011 | Washington | v | Sunderland Silksworth | 3 - 1 |
| Thu Sep 22nd,2011 | Brandon United | v | Horden CW | 1 - 3 |
| Sat Sep 24th,2011 | Annfield Plain | v | Seaham Red Star | 1 - 5 |
| Wed Sep 28th,2011 | Shildon | v | Sunderland West End | 7 - 0 |
| Sat Oct 1st,2011 | Coxhoe Athletic | v | Esh Winning | 0 - 6 |
| Sat Oct 1st,2011 | Jarrow FC | v | Tow Law Town | 4 - 2 |
| Sat Oct 29th,2011 | Stockton Town | v | Darlington FC | 0 - 2 |
| Mon Oct 31st,2011 | Gateshead | v | South Shields | 3 - 0 |
| Tue Nov 1st,2011 | Billingham Town | v | Darlington RA | 4 - 1 |
| Tue Nov 1st,2011 | Dunston UTS | v | Willington | 3 - 0 |
| Tue Nov 1st,2011 | Durham City | v | Sunderland RCA | 3 - 4 |
| Tue Nov 1st,2011 | Seaham Red Star | v | Peterlee Town | 4 - 0 |
| Tue Nov 1st,2011 | Whickham | v | Consett | 2 - 2 |
| Consett won 3-0 on penalties | ||||
| Wed Nov 2nd,2011 | Bishop Auckland | v | West Auckland Town | 2 - 6 |
| Wed Nov 2nd,2011 | Darlington CB | v | Esh Winning | 1 - 2 |
| Wed Nov 2nd,2011 | Horden CW | v | Crook Town | 1 - 2 |
| Wed Nov 2nd,2011 | Newton Aycliffe | v | Chester-le-Street | 3 - 0 |
| Wed Nov 2nd,2011 | Ryhope CW | v | Washington | 5 - 2 |
| Wed Nov 2nd,2011 | Shildon | v | Hartlepool United | 5 - 1 |
| Wed Nov 2nd,2011 | Spennymoor Town | v | Billingham Synthonia | 3 - 1 |
| Sat Nov 5th,2011 | Jarrow FC | v | Norton & Stockton | 1 - 3 |
| Sat Nov 5th,2011 | Wolviston | v | Hartlepool FC | 1 - 5 |
| Tue Jan 10th,2012 | Billingham Town | v | Dunston UTS | 1 - 0 |
| Tue Jan 10th,2012 | Seaham Red Star | v | Esh Winning | 0 - 5 |
| Tue Jan 10th,2012 | Sunderland RCA | v | Spennymoor Town | 0 - 2 |
| Tue Jan 10th,2012 | West Auckland Town | v | Consett | 2 - 3 |
| Wed Jan 11th,2012 | Newton Aycliffe | v | Shildon | 0 - 1 |
| Wed Jan 11th,2012 | Norton & Stockton | v | Gateshead | 1 - 3 |
| Wed Jan 11th,2012 | Ryhope CW | v | Crook Town | 2 - 0 |
| Sat Jan 14th,2012 | Darlington FC | v | Hartlepool FC |
| Mon Jan 30th,2012 | Gateshead | v | Shildon | 3 - 1 |
| Tue Jan 31st,2012 | Billingham Town | v | Consett | 4 - 0 |
| Tue Jan 31st,2012 | Ryhope CW | v | Spennymoor Town | 2 - 3 |
| Wed Feb 1st,2012 | Esh Winning | v | Hartlepool | 2 - 0 |
| Gateshead | v | Billingham Town | ||
| Spennymoor Town | v | Esh Winning |