| Sat Aug 19th,2000 | Jarrow Roofing | H | NL | 1 - 1 | M. Taylor |
| Tue Aug 22nd,2000 | Morpeth Town | A | NL | 6 - 0 | M. Taylor (3), Gray, Foreman, Sowerby |
| Sat Aug 26th,2000 | Durham City | H | NL | 0 - 1 | |
| Mon Aug 28th,2000 | Seaham Red Star | A | NL | 2 - 4 | Shields, Turner |
| Sat Sep 2nd,2000 | Liversedge | A | FAC | 1 - 1 | G. McDonald |
| Tue Sep 5th,2000 | Liversedge | H | FAC | 0 - 3 | |
| Sat Sep 9th,2000 | Hebburn Town | H | NL | 3 - 0 | Shields, G. McDonald (2) |
| Sat Sep 16th,2000 | Brandon United | H | NL | 2 - 3 | Bainbridge, G. McDonald |
| Sat Sep 23rd,2000 | Hallam | H | FAV | 2 - 0 | M. Taylor, G. McDonald |
| Sat Sep 30th,2000 | Newcastle Blue Star | H | NLC | 2 - 5 | G. McDonald (2, 1 pen) |
| Sat Oct 7th,2000 | Easington Colliery | A | NL | 0 - 4 | |
| Sat Oct 21st,2000 | Pickering Town | H | FAV | 0 - 1 | |
| Tue Oct 24th,2000 | Peterlee Newtown | H | DCC | 3 - 1 | Shields, Heggarty (2) |
| Sat Oct 28th,2000 | Peterlee Newtown | H | NL | 0 - 1 | |
| Sat Nov 4th,2000 | Tow Law Town | A | NL | 2 - 1 | Turner (pen), Shields |
| Sat Nov 11th,2000 | Brandon United | A | NL | 2 - 0 | Shields, C. Bone |
| Tue Nov 14th,2000 | Brandon United | H | DCC | 1 - 1 | G. McDonald (Lost 4-3 on pens) |
| Sat Nov 18th,2000 | Billingham Synthonia | H | NL | 1 - 2 | Bryson |
| Sat Dec 2nd,2000 | Consett | H | NL | 0 - 1 | |
| Sat Dec 9th,2000 | Guisborough Town | A | NL | 3 - 0 | Shields (2), Sowerby |
| Wed Dec 13th,2000 | Bedlington Terriers | H | NL | 1 - 2 | Croft |
| Sat Dec 16th,2000 | Jarrow Roofing | A | NL | 1 - 3 | Heggarty |
| Sat Dec 23rd,2000 | Morpeth Town | H | NL | 3 - 2 | Maw, Turner (pen), Leadbitter |
| Tue Dec 26th,2000 | Durham City | A | NL | 1 - 2 | Bryson |
| Sat Jan 6th,2001 | Whitley Bay | A | NL | 3 - 1 | Sowerby, Lumsden, Heggarty |
| Sat Jan 13th,2001 | Hebburn Town | A | NL | 3 - 0 | Heggarty, Shields, Lumsden |
| Tue Jan 30th,2001 | Tow Law Town | H | NL | 4 - 0 | Bowes (2), Turner (pen), Errington |
| Tue Feb 13th,2001 | Guisborough Town | H | NL | 1 - 0 | Maw |
| Tue Feb 20th,2001 | Dunston Federation | A | NL | 0 - 1 | |
| Sat Feb 24th,2001 | Peterlee Newtown | A | NL | 1 - 3 | Bowes |
| Tue Mar 6th,2001 | Seaham Red Star | H | NL | 2 - 0 | Bowes, Conlon |
| Sat Mar 10th,2001 | West Auckland | H | NL | 3 - 4 | Turner (pen), Heggarty (2) |
| Wed Mar 14th,2001 | Crook Town | A | NL | 2 - 1 | Turner, Gray |
| Sat Mar 17th,2001 | Billingham Town | A | NL | 0 - 1 | |
| Sat Mar 24th,2001 | West Auckland | A | NL | 3 - 0 | C. Bone, Bowes, Hanson |
| Tue Mar 27th,2001 | Marske United | H | NL | 1 - 4 | Bowes (pen) |
| Sat Mar 31st,2001 | Dunston Federation | H | NL | 1 - 1 | Bowes (pen) |
| Tue Apr 3rd,2001 | Newcastle Blue Star | H | NL | 0 - 0 | |
| Sat Apr 7th,2001 | Billingham Synthonia | A | NL | 1 - 1 | Hannah |
| Wed Apr 11th,2001 | Bedlington Terriers | A | NL | 0 - 2 | |
| Sat Apr 14th,2001 | Crook Town | H | NL | 1 - 2 | Heggarty |
| Mon Apr 16th,2001 | Billingham Town | H | NL | 2 - 3 | Bowes, Leadbitter |
| Sat Apr 21st,2001 | Consett | A | NL | 0 - 2 | |
| Thu Apr 26th,2001 | Easington Colliery | H | NL | 2 - 6 | Turner, Hannah |
| Sat Apr 28th,2001 | Whitley Bay | H | NL | 1 - 1 | Croft |
| Mon Apr 30th,2001 | Marske United | A | NL | 1 - 2 | Maw |
| Sat May 5th,2001 | Newcastle Blue Star | A | NL | 1 - 2 | Maw |